Post-translational modifications are crucial in modulation of biological functions and thus are interesting targets for protein analysis. Other modifications can be introduced during recombinant protein production or subsequent purification and handling steps like advanced glycation end products (AGE) and others. They need to be monitored to ensure consistency of production batches.
As PTMs and other modifications cover a wide range of physicochemical properties, the strategies for their analyses can cover different techniques like electrophoresis, mass spectrometry and Edman sequencing. Please consult us to discuss your project's specific requirements.